Recommended positive controls: HeLa whole cell lysate.
The PA1-29969 immunogen is: Peptide corresponding to amino acids 549 to 569 of human IL-1RAcP, which differs from the sequence ofmouse origin by three amino acids (1).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a component of the interleukin 1 receptor complex, which initiates signaling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
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Protein Aliases: hide; IL 1R 3; IL 1R3; IL 1RAcP; IL 1RAP; IL-1 receptor accessory protein; IL-1R-3; IL-1R3; IL1RAcP; ILN; Interleukin; Interleukin-1 receptor 3; Interleukin-1 receptor accessory protein; interleukin-1 receptor accessory protein beta
Gene Aliases: C3orf13; IL-1RAcP; IL1R3; IL1RAP
UniProt ID: (Human) Q9NPH3
Entrez Gene ID: (Human) 3556
Molecular Function: transmembrane signal receptor