|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|ELISA (ELISA)||See 7 publications below|
|Neutralization (Neu)||See 4 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Mouse|
|Published species reactivity||Rat Mouse|
|Host / Isotype||Rat / IgG2a|
|Immunogen||Recombinant mouse IL-2|
|Purification||Caprylic acid precipitation|
MM100 targets IL-2 in Western blot and ELISA applications and shows reactivity with mouse samples.
The MM100 immunogen is recombinant mouse IL-2.
MM100 detects IL-2 which has a predicted molecular weight of approximately 17 kDa.
This antibody is produced by injecting Rat IgG secreting hybridoma cells into the peritoneum of mice. The resulting ascites is collected from the mice and the antibody is purified.
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IL-2; Interleukin-2; T-cell growth factor; TCGF
Gene Aliases: Il-2; Il2
UniProt ID: (Mouse) P04351
Entrez Gene ID: (Mouse) 16183
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