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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||Recombinant human IL-2.|
|Storage buffer||PBS, pH 7.5|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Dot blot (DB)||Assay Dependent|
|Inhibition Assays (IA)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Neutralization (Neu)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Purity is >95% by SDS-PAGE. Kd: 1.8 x 10^-9
This product can inhibit the binding of IL-2 on p55 receptor.
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
TCGF, lymphokine, IL-2
T cell growth factor, aldesleukin, interleukin-2, involved in regulation of T-cell clonal expansion, TCGF