In ELISAs, this antibody does not cross-react with recombinant human (rh) IL-17E, rmIL-17, IL-17B, C, D, or F.
Reconstitute at 0.5 mg/mL in sterile PBS.
Interleukin 25 (IL-25) is a member of the IL-17 family and is identified as a proinflammatory cytokine which is produced by Th17 effector cells thus enabling the Th17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis. IL-25 also induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. IL-25 itself is activated through IL-23, IL-5, and TGF-beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IL17E; IL25; interleukin 17E; interleukin 25; interleukin-17E; interleukin-25
Gene Aliases: IL-17e; Il17e
Entrez Gene ID: (Mouse) 140806