Product References
GM-CSF-activated human dendritic cells promote type 1 T follicular helper cell polarization in a CD40-dependent manner.
Journal of cell science
Korniotis S,Saichi M,Trichot C,Hoffmann C,Amblard E,Viguier A,Grondin S,Noel F,Mattoo H,Soumelis V
17-7049-42 was used in Flow cytometry/Cell sorting to report that human blood CD1c+ dendritic cells activated by GM-CSF (also known as CSF2) drive the differentiation of naive CD4+ T cells into Tfh1 cells.
Tue Nov 01 00:00:00 EDT 2022
Dysregulated Peripheral Invariant Natural Killer T Cells in Plaque Psoriasis Patients.
Frontiers in cell and developmental biology
Hu Y,Chen Y,Chen Z,Zhang X,Guo C,Yu Z,Xu P,Sun L,Zhou X,Gong Y,Yu Q,Shi Y
Published figure using IL-4 monoclonal antibody (Product # 17-7049-42) in Flow Cytometry
Wed Feb 23 00:00:00 EST 2022
Cord Blood T Cells Expressing High and Low PKCζ Levels Develop into Cells with a Propensity to Display Th1 and Th9 Cytokine Profiles, Respectively.
International journal of molecular sciences
Perveen K,Quach A,McPhee A,Prescott SL,Barry SC,Hii CS,Ferrante A
Published figure using IL-4 monoclonal antibody (Product # 17-7049-42) in Flow Cytometry
Wed May 05 00:00:00 EDT 2021
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
Published figure using IL-4 monoclonal antibody (Product # 17-7049-42) in Flow Cytometry
Mon May 31 00:00:00 EDT 2021
Platelet-Derived GARP Induces Peripheral Regulatory T Cells-Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis.
Cancers
Zimmer N,Krebs FK,Zimmer S,Mitzel-Rink H,Kumm EJ,Jurk K,Grabbe S,Loquai C,Tuettenberg A
17-7049 was used in Flow cytometry/Cell sorting to show peripheral regulatory T cells can be induced by platelets through GARP and could explain why poor prognosis and metastasis are associated with high counts of circulating platelets.
Sat Dec 05 00:00:00 EST 2020
Platelet-Derived GARP Induces Peripheral Regulatory T Cells-Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis.
Cancers
Zimmer N,Krebs FK,Zimmer S,Mitzel-Rink H,Kumm EJ,Jurk K,Grabbe S,Loquai C,Tuettenberg A
17-7049 was used in Flow cytometry/Cell sorting to show peripheral regulatory T cells can be induced by platelets through GARP and could explain why poor prognosis and metastasis are associated with high counts of circulating platelets.
Sat Dec 05 00:00:00 EST 2020
Standardized 11-color flow cytometry panel for the functional phenotyping of human T regulatory cells.
Journal of biological methods
Manuszak C,Brainard M,Thrash E,Hodi FS,Severgnini M
Published figure using IL-4 monoclonal antibody (Product # 17-7049-42) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Concomitant suppression of TH2 and TH17 cell responses in allergic asthma by targeting retinoic acid receptor-related orphan receptor γt.
The Journal of allergy and clinical immunology
Na H,Lim H,Choi G,Kim BK,Kim SH,Chang YS,Nurieva R,Dong C,Chang SH,Chung Y
17-7049 was used in Flow cytometry/Cell sorting to determine the role of the TH17 cell pathway in regulating TH2 cell responses in allergic asthma.
Fri Jun 01 00:00:00 EDT 2018
CD4 T cell loss and Th2 and Th17 bias are associated with the severity of severe fever with thrombocytopenia syndrome (SFTS).
Clinical immunology (Orlando, Fla.)
Li MM,Zhang WJ,Weng XF,Li MY,Liu J,Xiong Y,Xiong SE,Zou CC,Wang H,Lu MJ,Yang DL,Peng C,Zheng X
Published figure using IL-4 monoclonal antibody (Product # 17-7049-42) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
The Genetic Polymorphisms of NLRP3 Inflammasome Associated with T Helper Cells in Patients with Multiple Myeloma.
Journal of immunology research
Zhao X,Hua M,Yan S,Yu J,Han F,Zhong C,Wang R,Zhang C,Hou M,Ma D
17-7049 was used in Flow cytometry/Cell sorting to investigate the role of the NLRP3 inflammasome in multiple myeloma.
Fri Nov 09 00:00:00 EST 2018
Effects of Anti-Integrin Treatment With Vedolizumab on Immune Pathways and Cytokines in Inflammatory Bowel Diseases.
Frontiers in immunology
Rath T,Billmeier U,Ferrazzi F,Vieth M,Ekici A,Neurath MF,Atreya R
17-7049 was used in Flow cytometry/Cell sorting to identify genetic, cellular, and immunological mechanisms that define response and failure to vedolizumab treatment.
Mon Sep 09 00:00:00 EDT 2019
The Phenotype of Monocytes in Anterior Uveitis Depends on the HLA-B27 Status.
Frontiers in immunology
Kasper M,Walscheid K,Laffer B,Bauer D,Busch M,Wildschütz L,Wang B,Loser K,Vogl T,Grajewski RS,Langmann T,Heiligenhaus A
Mon Sep 16 00:00:00 EDT 2019
Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis.
Frontiers in immunology
Hou TY,Chen MR,Chou YC,Kan PC,Tsai YT,Cha TL
Published figure using IL-4 monoclonal antibody (Product # 17-7049-42) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia.
Oncoimmunology
Catakovic K,Gassner FJ,Ratswohl C,Zaborsky N,Rebhandl S,Schubert M,Steiner M,Gutjahr JC,Pleyer L,Egle A,Hartmann TN,Greil R,Geisberger R
17-7049 was used in Flow cytometry/Cell sorting to reveal that TIGIT+CD4+T cells provide a supportive microenvironment for CLL cells.
Sat Jan 29 00:00:00 EST 2022
Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis.
The Journal of clinical investigation
Millet A,Martin KR,Bonnefoy F,Saas P,Mocek J,Alkan M,Terrier B,Kerstein A,Tamassia N,Satyanarayanan SK,Ariel A,Ribeil JA,Guillevin L,Cassatella MA,Mueller A,Thieblemont N,Lamprecht P,Mouthon L,Perruche S,Witko-Sarsat V
17-7049 was used in Flow cytometry/Cell sorting to investigate disruption of immune silencing by proteinase 3 on apoptotic cells.
Mon Nov 02 00:00:00 EST 2015
A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomes.
Nucleic acids research
Zhong F,Zhou N,Wu K,Guo Y,Tan W,Zhang H,Zhang X,Geng G,Pan T,Luo H,Zhang Y,Xu Z,Liu J,Liu B,Gao W,Liu C,Ren L,Li J,Zhou J,Zhang H
Wed Dec 02 00:00:00 EST 2015
DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.
Human molecular genetics
Volk T,Pannicke U,Reisli I,Bulashevska A,Ritter J,Björkman A,Schäffer AA,Fliegauf M,Sayar EH,Salzer U,Fisch P,Pfeifer D,Di Virgilio M,Cao H,Yang F,Zimmermann K,Keles S,Caliskaner Z,Güner SÜ,Schindler D,Hammarström L,Rizzi M,Hummel M,Pan-Hammarström Q,Schwarz K,Grimbacher B
17-7049 was used in Flow cytometry/Cell sorting to investigate the range of phenotypes associated with DCLRE1C (ARTEMIS) mutations in humans.
Sun Dec 20 00:00:00 EST 2015
CD4+ T cells contain early extrapulmonary tuberculosis (TB) dissemination and rapid TB progression and sustain multieffector functions of CD8+ T and CD3- lymphocytes: mechanisms of CD4+ T cell immunity.
Journal of immunology (Baltimore, Md. : 1950)
Yao S,Huang D,Chen CY,Halliday L,Wang RC,Chen ZW
17-7049 was used in Flow cytometry/Cell sorting to investigate the possibility that CD4(+) T cells can act as innate-like cells to contain very early Mycobacterium tuberculosis dissemination using CD4-depleted macaques.
Sat Mar 01 00:00:00 EST 2014
A polymorphism in TIM1 is associated with susceptibility to severe hepatitis A virus infection in humans.
The Journal of clinical investigation
Kim HY,Eyheramonho MB,Pichavant M,Gonzalez Cambaceres C,Matangkasombut P,Cervio G,Kuperman S,Moreiro R,Konduru K,Manangeeswaran M,Freeman GJ,Kaplan GG,DeKruyff RH,Umetsu DT,Rosenzweig SD
17-7049 was used in Flow cytometry/Cell sorting to investigate the variability in hepatitis disease severity.
Tue Mar 01 00:00:00 EST 2011