|Tested species reactivity||Rat|
|Published species reactivity||Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant rat IL-6|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PR627 targets IL-6 in WB applications and shows reactivity with Rat samples.
The PR627 immunogen is recombinant rat IL-6.
PR627 detects IL-6 which has a predicted molecular weight of approximately 22 kDa.
This product is a Low Endotoxin formulation.
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protective effects of Lactobacillus paracasei F19 in a rat model of oxidative and metabolic hepatic injury.
PR627 was used in western blot to investigate the protective effect of Lactobacillus paracasei F19 against liver injury in rats
|Nardone G,Compare D,Liguori E,Di Mauro V,Rocco A,Barone M,Napoli A,Lapi D,Iovene MR,Colantuoni A||American journal of physiology. Gastrointestinal and liver physiology (299:G669)||2010|
Morphological and immunological evidence of a unique selective production and endoplasmic reticular accumulation of interleukin-1alpha in rat peritoneal macrophages induced by Pseudomonas aeruginosa exotoxin A.
PR627 was used in immunocytochemistry to study the selective production and endoplasmic reticular accumulation of IL-1alpha induced by Pseudomonas aeruginosa exotoxin A in rat peritoneal macrophages
|Huang YT,Jeng CR,Cheng CH,Chueh LL,Liu JJ,Pang VF||Cellular immunology (221:143)||2003|