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|Tested species reactivity||Human|
|Published species reactivity||Mouse , Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant human IL-6.|
|Storage buffer||PBS, pH 7.5|
|Contains||0.5% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This product is recommended as a capture antibody in Sandwich ELISA applications.
Interleukin 6 is a cytokine secreted by T cells and macrophages, has shown to exhibit activity in response to tissue damage and infection. They have also been found to be involved in various other activities like development of blood, cancer, embryonic development, and regulation of the immune system. IL6 is included in a family of other cytokines which include ciliary neurotrophic factor, cardiotrophin-1, leukemia inhibitory factor and interleukin 11. IL-6 can bring about differentiation through a receptor system which requires a specific receptor and a signaling subunit, gp130.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Atomic force microscopy analysis of IgG films at hydrophobic surfaces: a promising method to probe IgG orientations and optimize ELISA tests performance.
AHC0562 was used in ELISA and immunocytochemistry to study IgG monolayers using atomic force microscopy analyses
|de Thier P,Bacharouche J,Duval JF,Skali-Lami S,Francius G||Biochimica et biophysica acta (1854:138)||2015|
Dopamine receptors in human adipocytes: expression and functions.
AHC0562 was used in ELISA to measure dopamine receptor and arylsulfatase A expression in human adipose tissue and determine if dopamine regulates prolactin and adipokine expression and release.
|Borcherding DC,Hugo ER,Idelman G,De Silva A,Richtand NW,Loftus J,Ben-Jonathan N||PloS one (6:null)||2011|
Insulin stimulates interleukin-6 expression and release in LS14 human adipocytes through multiple signaling pathways.
AHC0562 was used in ELISA to determine the mechanisms by which insulin stimulates IL-6 production and release in preadipocytes.
|LaPensee CR,Hugo ER,Ben-Jonathan N||Endocrinology (149:5415)||2008|
Biological characterization of lipopolysaccharide from Treponema pectinovorum.
||Kesavalu L,Falk CW,Davis KJ,Steffen MJ,Xu X,Holt SC,Ebersole JL||Infection and immunity (70:211)||2002|
Cytokine responses to treponema pectinovorum and treponema denticola in human gingival fibroblasts.
||Nixon CS,Steffen MJ,Ebersole JL||Infection and immunity (68:5284)||2000|
HSF, IFNB2, IL-6, HGF, BSF2
B-cell differentiation factor, B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, IFN-beta-2, hybridoma growth factor, interferon beta-2, interleukin BSF-2, interleukin-6, interleukin HP-1, BSF2, HGF, HSF, IFNB2