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|Tested species reactivity||Pig|
|Published species reactivity||Pig|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant porcine IL-8|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 4 publications below|
MP800 targets IL-8 in WB applications and shows reactivity with Porcine samples.
The MP800 immunogen is recombinant porcine IL-8.
MP800 detects IL-8 which has a predicted molecular weight of approximately 9 kDa.
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Does nanocrystalline silver have a transferable effect?
MP800 was used in immunohistochemistry to study the antiinflammatory effect of nanocrystalline silver
|Nadworny PL,Landry BK,Wang J,Tredget EE,Burrell RE||Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society (18:254)||2010|
Anti-inflammatory activity of nanocrystalline silver-derived solutions in porcine contact dermatitis.
MP800 was used in immunohistochemistry to evaulate the benefit of nanocrystalline silver in porcine contact dermatitis
|Nadworny PL,Wang J,Tredget EE,Burrell RE||Journal of inflammation (London, England) (7:null)||2010|
Histopathological and immunohistochemical findings in the lungs of pigs infected experimentally with Mycoplasma hyopneumoniae.
MP800 was used in immunohistochemistry to study the histopathology and immunohistochemistry of lung lesions in Mycoplasma hyopneumoniae-infected pigs
|Redondo E,Masot AJ,Fern?ndez A,G?zquez A||Journal of comparative pathology (140:260)||2009|
Laser-assisted microdissection and real-time PCR detect anti-inflammatory effect of perfluorocarbon.
MP800 was used in immunohistochemistry to investigate the cells involved in inflammation prevention induced by perfluorocarbon
|von der Hardt K,Kandler MA,Fink L,Schoof E,Dotsch J,Bohle RM,Rascher W||American journal of physiology. Lung cellular and molecular physiology (285:L55)||2003|
alveolar macrophage chemotactic factor I; alveolar macrophage-derived chemotactic factor-I; C-X-C motif chemokine 8; IL-8; interleukin-8
Signal transduction Cell surface receptor mediated signal transduction Cytokine and chemokine mediated signaling pathway Intracellular signaling cascade Calcium mediated signaling NF-kappaB cascade Cell communication Ligand-mediated signaling Immunity and defense T-cell mediated immunity Granulocyte-mediated immunity Macrophage-mediated immunity Developmental processes Mesoderm development Angiogenesis Cell structure and motility Cell motility Cell proliferation and differentiation