Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Interleukin 9 (IL9) is a cytokine that regulates a variety of hematopoietic cells. It is secreted by T-cells, and supports IL-2 independent, and IL-4 independent growth of helper T-cells. It is also a positive regulator of cell proliferation, and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates signal transducer and activator (STAT) proteins and results in IRS1 and IRS2/PI3K and MEK/ERK signaling cascades.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytokine P40; homolog of mouse T cell and mast cell growth factor 40; IL-9; Interleukin-9; p40 cytokine; p40 T-cell and mast cell growth factor; T-cell growth factor P40
Gene Aliases: HP40; IL-9; IL9; P40
UniProt ID: (Human) P15248
Entrez Gene ID: (Human) 3578