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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Purified recombinant human IL-1-alpha|
|Storage buffer||PBS, pH 7.5|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|ELISA (ELISA)||See 1 publications below|
This product is recommended as a capture antibody in Sandwich ELISA applications.
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Human||Not Cited||Cytokine responses to treponema pectinovorum and treponema denticola in human gingival fibroblasts.||Nixon CS,Steffen MJ,Ebersole JL||Infection and immunity (68:5284)||2000|
CTLA8; cytotoxic T-lymphocyte-associated serine esterase 8; hematopoietin-1; IL-1 alpha; IL17; interleukin 1, alpha; interleukin 17; preinterleukin 1 alpha; pro-interleukin-1-alpha
IL-1A; IL1; IL1-ALPHA; IL1A; IL1F1