This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Mouse IL11RA/IL11Ra.
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Enhancer trap locus homolog 2; Etl-2; IL-11 receptor subunit alpha-1; IL-11R subunit alpha-1; IL-11R-alpha-1; Il-11ra-alpha; IL-11RA1; interleukin 11 receptor, alpha chain 2; Interleukin-11 receptor subunit alpha-1; locus 2; Novel cytokine receptor 1; NR-1; sIL11RA; Soluble form
Gene Aliases: AI314697; Etl2; GP130; Il-11ra; Il11ra; Il11ra1; Il11ra2; NR1
UniProt ID: (Mouse) Q64385
Entrez Gene ID: (Mouse) 16157