|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 102 and 427 of Human IL13 Receptor alpha 1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28309 targets IL13 Receptor alpha 1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28309 immunogen is recombinant fragment corresponding to a region within amino acids 102 and 427 of Human IL13 Receptor alpha 1.
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cancer/testis antigen 19; CD213A1; CD213a1 antigen; CT19; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13Ra; IL-13RA1; IL13 receptor alpha-1 chain; Interleukin 13 receptor; interleukin 13 receptor, alpha 1; Interleukin-13 receptor subunit alpha-1
Gene Aliases: CD213A1; CT19; IL-13Ra; IL13R; IL13RA; IL13RA1; NR4
UniProt ID: (Human) P78552
Entrez Gene ID: (Human) 3597
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