Cytokines that signal through Class II receptors form a distinct family that includes the interferons and interleukin 10 (IL-10). Recent identification of several IL-10 homologs has defined a cytokine subfamily that includes AK155, IL-19, IL-20, IL-22, and IL-24. IL-20 belongs to the IL-10 family and plays a role in skin inflammation and the development of hematopoietic cells. Little is known about its other biological functions and clinical implications. These cytokines display pro-inflammatory activities in different tissues, including skin.
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Protein Aliases: Cytokine Zcyto10; four alpha helix cytokine; IL-20; IL10D; Interleukin-20; ZCYTO10
Gene Aliases: IL-20; IL10D; IL20; UNQ852/PRO1801; ZCYTO10
UniProt ID: (Human) Q9NYY1
Entrez Gene ID: (Human) 50604