Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:200-1:1,000 | - |
Flow Cytometry (Flow) |
1:200 - 1:400 | - |
ELISA (ELISA) |
1:10,000 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Non-human primate, Rat |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
3A9 |
Immunogen |
Purified recombinant fragment of human ILK (amino acids: 97-244) expressed in E. Coli. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
Conc. Not Determined |
Storage buffer |
ascites |
Contains |
0.03% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2538570 |
MA5-17099 targets ILK in FACS, IHC, and WB applications and shows reactivity with Human, Mouse, and Non-human primate samples.
The MA5-17099 immunogen is purified recombinant fragment of human ILK (amino acids: 97-244) expressed in E. Coli.
MA5-17099 detects ILK which has a predicted molecular weight of approximately 51.4kDa.
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 59 kDa serine/threonine-protein kinase; Beta-integrin-linked kinase; epididymis secretory protein Li 28; ILK-1; ILK-2; integrin binding protein kinase; Integrin linked ILK; integrin linked kinase; integrin-linked kinase; integrin-linked kinase-2; Integrin-linked protein kinase; p59ILK
Gene Aliases: AA511515; ESTM24; HEL-S-28; ILK; ILK-1; ILK-2; ILK1; ILK2; P59; p59ILK
UniProt ID: (Human) Q13418, (Mouse) O55222, (Rat) Q99J82
Entrez Gene ID: (Human) 3611, (Mouse) 16202, (Rat) 170922
Molecular Function:
non-receptor serine/threonine protein kinase
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