This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
MA5-17099 targets ILK in FACS, IHC, and WB applications and shows reactivity with Human, Mouse, and Non-human primate samples.
The MA5-17099 immunogen is purified recombinant fragment of human ILK (amino acids: 97-244) expressed in E. Coli.
MA5-17099 detects ILK which has a predicted molecular weight of approximately 51.4kDa.
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 59 kDa serine/threonine-protein kinase; epididymis secretory protein Li 28; ILK-1; ILK-2; integrin binding protein kinase; integrin linked kinase; integrin-linked kinase; integrin-linked kinase-2; Integrin-linked protein kinase; p59ILK
Gene Aliases: AA511515; ESTM24; HEL-S-28; ILK; ILK-1; ILK-2; ILK1; ILK2; P59; p59ILK