SAC2 is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.
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Protein Aliases: EC 220.127.116.11; hSAC2; Inositol polyphosphate 5 phosphatase OCRL 1; Inositol polyphosphate 5 phosphatase OCRL1; Inositol polyphosphate 5-phosphatase F; INPP5F; LOCR; NPHL2; OCRL; OCRL 1; OCRL1; OCRL_HUMAN; Oculocerebrorenal syndrome of Lowe; Phosphatidylinositide phosphatase SAC2; Phosphatidylinositol polyphosphate 5 phosphatase; Sac domain-containing inositol phosphatase 2; Sac domain-containing phosphoinositide 4-phosphatase 2; sac domain-containing phosphoinositide 5-phosphatase 2
Gene Aliases: 5830435P03Rik; AI115354; AW561896; cI-27; hSAC2; INPP5F; KIAA0966; mKIAA0966; MSTP007; MSTP047; MSTPO47; SAC2