MA5-13783 targets Insulin Receptor beta in ELISA, ICC/IF, IHC (P), Affinity Purification, and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples.
The MA5-13783 immunogen is recombinant-fragment including the C-terminal 100 amino acids of human insulin receptor.
The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a beta-alpha-alpha-beta configuration. The beta-subunit (95kDa) possesses a single transmembrane domain with tyrosine kinase acivity, whereas the alpha-subunit (135kDa) is completely extracellular.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD220; CD220 beta; HHF5; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR beta
Gene Aliases: 4932439J01Rik; CD220; D630014A15Rik; HHF5; INSR; IR; IR-A; IR-B