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|Tested species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-2 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale, and purified with Protein A.
ABfinity™ monoclonal antibodies resemble rabbit monoclonals isolated from serum or produced by hybridomas, but demonstrate greater specificity and sensitivity. Because ABfinity™ recombinant antibodies are derived from cloned DNA sequences of the heavy and light antibody chains, they are not susceptible to cell-line drift or lot-to-lot variation, thus allowing for peak specificity and performance.
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
IP-10 is a 10 kDa protein. It is a member of the CXC family and acts by binding to CXCR3. It is a pro-inflammatory chemoattractant cytokine that attracts activated T lymphocytes. IP-10 is constitutively expressed at low levels in lymph organs, and the expression is highly induced by IFN- gamma and to some extent by IL12. It is an important biomarker for diagnosis of many clinical conditions, and it plays an important role in host defense and inflammation. IP-10 exhibits an angiostatic and an antitumor role.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
10 kDa interferon gamma-induced protein; C-X-C motif chemokine 10; CRG-2; gamma-IP10; gIP-10; Ifi10; INP10; interferon activated gene 10; Interferon Gamma Inducible Protein 10; interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; IP-10; IP10; mob-1; Scyb10; small inducible cytokine B subfamily (Cys-X-Cys), member 10; small-inducible cytokine B10
C7; CRG-2; Crg2; Cxcl10; gIP-10; Ifi10; INP10; IP-10; IP10; mob-1; Scyb10