|Tested species reactivity||Bovine, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 93-107 of bovine IRAG.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
PA3-851 detects CARP from mouse and bovine samples.
PA3-851 has been successfully used in Western blot and immunocytochemistry procedures.
The PA3-851 immunogen is a synthetic peptide corresponding to residues 93-107 of bovine IRAG.
IP3R-associated cGMP kinase substrate (IRAG) is a 125 kDa protein found to be an essential regulator of intercellular calcium release.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta.
PA3-851 was used in immunoprecipitation and western blot to investigate the mediation of intracellular calcium by a complex formed by IRAG, IP3 receptor, and cGMP kinase I beta
|Schlossmann J,Ammendola A,Ashman K,Zong X,Huber A,Neubauer G,Wang GX,Allescher HD,Korth M,Wilm M,Hofmann F,Ruth P||Nature (404:197)||2000|