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|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein derived from amino acids 207-452 of the murine IRF7 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||0.1-1.0 ug/ml|
|Gel Shift (GS)||0.2-1.0 ug per 5 ul|
|Immunofluorescence (IF)||10 ug/ml|
|Immunoprecipitation (IP)||3.0-5.0 ug per 1x10^7 cells extract|
|Western Blot (WB)||0.5-2.0 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Mouse||Not Cited||Tissue-specific positive feedback requirements for production of type I interferon following virus infection.||Prakash A,Smith E,Lee CK,Levy DE||The Journal of biological chemistry (280:18651)||2005|
interferon regulatory factor 7; interferon regulatory factor-7H; IRF-7; IRF-7H; IRF7A