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Product Details
MA1-80920
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Guinea pig,
Human,
Pig
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
Y9A2
Immunogen
alpha9 integrin transfected lambda cells.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2128459
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Mouse anti Human Integrin alpha 9 beta 1 antibody, clone Y9A2 recognizes the human alpha9 integrin, a approximately 140 kDa glycoprotein expressed as a heterodimer in association with the beta1 integrin.
Target Information
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD29; Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; integrin alpha 9; Integrin alpha-9; Integrin alpha-RLC; integrin beta 1; Integrin beta-1; integrin beta-1 subunit; Integrin beta1; integrin VLA-4 beta subunit; integrin, alpha 9; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); very late activation protein, beta polypeptide; VLA-4 subunit beta
Gene Aliases: ALPHA-RLC; CD29; FNRB; GPIIA; ITGA4L; ITGA9; ITGB1; MDF2; MSK12; RLC; VLA-BETA; VLAB
UniProt ID: (Human) Q13797, (Pig) Q9GLP0, (Human) P05556
Entrez Gene ID: (Pig) 100626707, (Human) 3680, (Pig) 397019, (Human) 3688, (Guinea pig) 100716659, (Guinea pig) 100719502
collagen binding
laminin binding
metal ion binding
signaling receptor activity
protein heterodimerization activity
virus receptor activity
glycoprotein binding
fibronectin binding
protease binding
actin binding
integrin binding
protein binding
coreceptor activity
protein kinase binding
protein domain specific binding
C-X3-C chemokine binding
protein complex binding
peptide binding
cell adhesion molecule binding
alpha-actinin binding
collagen binding involved in cell-matrix adhesion
cadherin binding involved in cell-cell adhesion
integrin
cell adhesion
integrin-mediated signaling pathway
extracellular matrix organization
neutrophil chemotaxis
wound healing
regulation of collagen catabolic process
positive regulation of cell migration
receptor internalization
cell adhesion mediated by integrin
cellular response to low-density lipoprotein particle stimulus
positive regulation of protein localization to plasma membrane
G1/S transition of mitotic cell cycle
in utero embryonic development
cell fate specification
tissue homeostasis
cell migration involved in sprouting angiogenesis
cellular calcium ion homeostasis
cellular defense response
homophilic cell adhesion via plasma membrane adhesion molecules
leukocyte cell-cell adhesion
cell-matrix adhesion
calcium-independent cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of cell proliferation
negative regulation of cell proliferation
germ cell migration
visual learning
positive regulation of cell-substrate adhesion
positive regulation of neuron projection development
response to activity
cell migration
formation of radial glial scaffolds
B cell differentiation
negative regulation of cell projection organization
cell-substrate adhesion
protein transport within lipid bilayer
cell-cell adhesion mediated by integrin
heterotypic cell-cell adhesion
response to gonadotropin
negative regulation of Rho protein signal transduction
response to drug
positive regulation of apoptotic process
stress fiber assembly
positive regulation of MAPK cascade
positive regulation of GTPase activity
sarcomere organization
negative regulation of neuron differentiation
positive regulation of endocytosis
viral entry into host cell
mesodermal cell differentiation
axon extension
dendrite morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
regulation of immune response
leukocyte migration
leukocyte tethering or rolling
regulation of cell cycle
cardiac muscle cell differentiation
maternal process involved in female pregnancy
bicellular tight junction assembly
cellular response to mechanical stimulus
cellular response to vitamin D
cellular response to ionizing radiation
positive regulation of establishment of protein localization to plasma membrane
negative regulation of anoikis
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