|Tested species reactivity||Human, Mouse, Non-human primate, Rabbit|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG2b|
|Immunogen||B10 mouse spleen cells enriched for T cells|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 9 publications below|
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Immunogenicity of undifferentiated and differentiated allogeneic mouse mesenchymal stem cells.
MA1-10081 was used in flow cytometry to study the immunogenicity and immunomodulatory properties of bone marrow-derived mesenchymal stem cells using an allogeneic mouse model.
|Mukonoweshuro B,Brown CJ,Fisher J,Ingham E||Journal of tissue engineering (5:null)||2014|
Dendritic cell differentiation potential of mouse monocytes: monocytes represent immediate precursors of CD8- and CD8+ splenic dendritic cells.
MA1-10081 was used in flow cytometry to discuss DC generation from monocytes.
|León B,Martínez del Hoyo G,Parrillas V,Vargas HH,Sánchez-Mateos P,Longo N,López-Bravo M,Ardavín C||Blood (103:2668)||2004|
Extensive proliferation of T cell lineage-restricted progenitors in the thymus: an essential process for clonal expression of diverse T cell receptor beta chains.
MA1-10081 was used in flow cytometry to assess the proliferative potential of thymic progenitors that are T cell lineage restricted.
|Kawamoto H,Ohmura K,Fujimoto S,Lu M,Ikawa T,Katsura Y||European journal of immunology (33:606)||2003|
Cell-intrinsic effects of non-MHC NOD genes on dendritic cell generation in vivo.
MA1-10081 was used in flow cytometry to characterize the differences in dendritic cell generation in vivo caused by non-MHC NOD genes.
|Prasad SJ,Goodnow CC||International immunology (14:677)||2002|
Immature multipotent hemopoietic progenitors lacking long-term bone marrow-reconstituting activity in the aorta-gonad-mesonephros region of murine day 10 fetuses.
MA1-10081 was used in flow cytometry to examine multipotent progenitors from early fetuses.
|Ohmura K,Kawamoto H,Lu M,Ikawa T,Ozaki S,Nakao K,Katsura Y||Journal of immunology (Baltimore, Md. : 1950) (166:3290)||2001|
Downmodulation of the inflammatory response to bacterial infection by gammadelta T cells cytotoxic for activated macrophages.
MA1-10081 was used in flow cytometry to propose that gammadelta T cells eliminating activated macrophages after infection with an intracellular pathogen.
|Egan PJ,Carding SR||The Journal of experimental medicine (191:2145)||2000|
Emergence of T, B, and myeloid lineage-committed as well as multipotent hemopoietic progenitors in the aorta-gonad-mesonephros region of day 10 fetuses of the mouse.
MA1-10081 was used in flow cytometry to investigate the aorta-gonad-mesonephros region as a source of hemopoietic progenitors.
|Ohmura K,Kawamoto H,Fujimoto S,Ozaki S,Nakao K,Katsura Y||Journal of immunology (Baltimore, Md. : 1950) (163:4788)||1999|
Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells.
MA1-10081 was used in flow cytometry to report that FcR is a useful marker to isolate the most immature population of murine fetal thymic cells.
|Hattori N,Kawamoto H,Katsura Y||The Journal of experimental medicine (184:1901)||1996|
Stimulation of the platelet-derived growth factor beta receptor signaling pathway activates protein kinase C-delta.
MA1-10081 was used in flow cytometry to study the contribution of PKC-delta in response to activation of a receptor tyrosine kinase.
|Li W,Yu JC,Michieli P,Beeler JF,Ellmore N,Heidaran MA,Pierce JH||Molecular and cellular biology (14:6727)||1994|