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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000 | View 1 publication 1 publication |
Flow Cytometry (Flow) |
1:10-1:50 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide between 156-186 amino acids from the central region of human ITGB1BP3 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
2 mg/mL |
Purification |
Ammonium sulfate precipitation, Size-exclusion - Dialysis |
Storage buffer |
PBS |
Contains |
0.09% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2542107 |
ITGB1BP3 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The protein reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. It is involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation and may play a role in the regulation of terminal myogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: integrin beta 1 binding protein 3; Integrin beta-1-binding protein 3; MIBP; Muscle integrin-binding protein; muscle-specific beta 1 integrin binding protein; Nicotinamide riboside kinase 2; Nicotinic acid riboside kinase 2; nmR-K 2; NRK 2; Ribosylnicotinamide kinase 2; Ribosylnicotinic acid kinase 2; RNK 2
Gene Aliases: 2310015C21Rik; ITGB1BP3; MIBP; NMRK2; NRK2
UniProt ID: (Human) Q9NPI5, (Mouse) Q9D7C9
Entrez Gene ID: (Human) 27231, (Mouse) 69564
Molecular Function:
nucleotide kinase
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