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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 185-414 of human ITPK1. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
3.8 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808803 |
Immunogen sequence: CVVQNFINHN AVLYKVFVVG ESYTVVQRPS LKNFSAGTSD RESIFFNSHN VSKPESSSVL TELDKIEGVF ERPSDEVIRE LSRALRQALG VSLFGIDIII NNQTGQHAVI DINAFPGYEG VSEFFTDLLN HIATVLQGQS TAMAATGDVA LLRHSKLLAE PAGGLVGERT CSASPGCCGS MMGQDAPWKA EADAGGTAKL PHQRLGCNAG VSPSFQQHCV ASLATKASSQ; Positive Samples: HeLa, HepG2, Mouse testis, Mouse brain, Mouse intestine, Rat brain
ITPK1 encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: inositol 1,3,4-triphosphate 5/6 kinase; Inositol 1,3,4-trisphosphate 5/6-kinase; Inositol-tetrakisphosphate 1-kinase; Inositol-triphosphate 5/6-kinase; ins(1,3,4)P(3) 5/6-kinase
Gene Aliases: BC031182; ITPK1; ITRPK1
UniProt ID: (Human) Q13572, (Mouse) Q8BYN3
Entrez Gene ID: (Human) 3705, (Rat) 500709, (Mouse) 217837
Molecular Function:
kinase
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