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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 1-30 amino acids from the C-terminal region of human Importin alpha-4 (KPNA4)|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
importin alpha Q1; Importin alpha-4 subunit; importin subunit alpha-3; importin subunit alpha-4; karyopherin alpha 4 (importin alpha 3); Karyopherin alpha-4 subunit; karyopherin subunit alpha-4; KPNA4; QIP1; Qip1 protein
1110058D08Rik; IPOA3; KPNA4; QIP1; SRP3