PA1-7223 detects the Influenza A virus.
PA1-7223 has been successfully used in immunofluorescence procedures.
The PA1-7223 immunogen is influenza A, Phillipines (H3N2).
Recommended short term storage (up to 6 months) is at 4°C. For longer storage, aliquot and freeze.
Influenza A virus is an enveloped virus encoding 10 polypeptides. RNA segment 7 encodes for two proteins: M1 (matrix 1) and M2 (matrix 2). M1 protein is encoded by an mRNA that is colinear, while M2 protein is synthesized from spliced mRNA. M2 protein is a transmembrane protein composed of three Domains: 1) 24 residues representing the N-terminal region, 2) 19 hydro-phobic residues that serve as a membrane anchor, and 3) 54 residues near the C-terminal in the cytoplasmic domain. The M2 protein has been found to play a role in Influenza replication and assembly of virion particles. Further experimentation has demonstrated that this protein is an acid-activated ion channel for virus replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H3N2; H3N2 M1; H3N2 Matrix protein; Influenza H3N2