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|Tested species reactivity||Virus|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Influenza A / Puerto Rico /8/34 (H1N1) and A/Bangkok /1/79 (H3N2) viruses.|
|Storage buffer||PBS, pH 7.5|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-23054 detects Influenza A Virus Nucleoprotein.
MA1-23054 has been successfully used in immunofluorescence procedures.
The MA1-23054 immunogen is influenza A / Puerto Rico /8/34 (H1N1) and A/Bangkok /1/79 (H3N2) strains.
The nucleoprotein (NP) of Influenza A virus encapsidates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.