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|Tested species reactivity||Bovine, Human, Pig|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Full length native protein (purified) (Human).|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-22711 detects Insulin in Human, Bovine and Porcine samples.
MA1-22711 has been successfully used in ELISA procedures.
MA1-22711 immunogen corresponds to Full length native protein (purified) (Human).
Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage,formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B or b-cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Ins; insulin; preproinsulin; proinsulin
BOS_25069; IDDM; IDDM1; IDDM2; ILPR; INS; IRDN; MODY10