|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Leukocytes of patient suffering from LGL-type leukaemia.|
|Storage buffer||PBS with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||10 µl / 100 µl whole blood or 10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Microparticles from stored red blood cells activate neutrophils and cause lung injury after hemorrhage and resuscitation.
MA1-19779 was used in immunocytochemistry to study the role of microparticles from stored red blood cells in activating neutrophils and causing lung injury after hemorrhage and resuscitation
|Belizaire RM,Prakash PS,Richter JR,Robinson BR,Edwards MJ,Caldwell CC,Lentsch AB,Pritts TA||Journal of the American College of Surgeons (214:648)||2012|