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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Integrin beta 3 (Human).|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Flow Cytometry (Flow)||1/50-1/100|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1/50-1/100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-21188 detects Integrin alpha 2b/beta 3 in Human samples.
MA1-21188 has been successfully used in ELISA, FACS, Immunohistochemistry, Immunoprecipitation and Western Blot procedures.
MA1-21188 immunogen corresponds to Integrin beta 3 (Human)..
The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
alphaIIb protein; antigen CD61; CD41; CD61; GP2B; GP3A; GPalpha IIb; GPIIb; GPIIIa; Integrin alpha-IIb; integrin beta 3; Integrin beta-3; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGA2B; ITGA3; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet membrane glycoprotein IIIa; platelet-specific antigen BAK; protein phosphatase 1, regulatory subunit 93
BDPLT16; BDPLT2; CD41; CD41B; CD61; GP2B; GP3A; GPIIb; GPIIIa; GT; GTA; HPA3; ITGA2B; ITGAB; ITGB3; PPP1R93