|Tested species reactivity||Human, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rat / IgG2b|
|Storage buffer||PBS, pH 7.4|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:50-1:100|
|Functional Assay (FN)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
This product is a low-endotoxin, preservative-free formulation.
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
CD49d, also known as integrin alpha-4 or VLA-4 subunit alpha, is a ~150kDa single pass type 1 transmembrane glycoprotein that contains seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa. CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue through its interaction with MadCam-1, preferentially expressed on Peyerâ€™s patch high endothelial venules and postcapillary venules in lamina propria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions.
MA1-82769 was used in immunocytochemistry and western blot to study the expression and distribution of three secretory carrier membrane proteins
|Singleton DR,Wu TT,Castle JD||Journal of cell science (110 ( Pt 17):2099)||1997|