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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||a6b4 integrin purified from A431 cells|
|Storage buffer||PBS, pH 7.4|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||10 µl for 10^6 cells in 100 µl|
|Immunohistochemistry (Frozen) (IHC (F))||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA1-34257 detects CD49f from human samples.
MA1-34257 has been successfully used in immunohistochemistry (frozen tissue) and Flow Cytometry applications.
The MA1-34257 immunogen is: a6b4 integrin purified from A431 cells
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Long-term stability and safety of transgenic cultured epidermal stem cells in gene therapy of junctional epidermolysis bullosa.
MA1-34257 was used in immunohistochemistry to investigate the stability and safety of transgenic cultured epidermal stem cells in skin disease gene therapy
|De Rosa L,Carulli S,Cocchiarella F,Quaglino D,Enzo E,Franchini E,Giannetti A,De Santis G,Recchia A,Pellegrini G,De Luca M||Stem cell reports (2:1)||2014|
CD49 antigen-like family member F; CD49f; integrin alpha 6; Integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6; ITGA6B; VLA-6
CD49f; ITGA6; ITGA6B; VLA-6