|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rat / IgG2a|
|Storage buffer||TBS, pH 8.0, with 10mg BSA|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (FACS)||Assay dependent.|
|Immunofluorescence (IF)||Assay dependent.|
|Immunohistochemistry (IHC)||Assay dependent.|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD44posCD49fhiCD133/2hi defines xenograft-initiating cells in estrogen receptor-negative breast cancer.
MA1-35230 was used in immunohistochemistry to identity the CD44posCD49fhiCD133/2hi cells as tumorigenic in murine xenograft models
|Meyer MJ,Fleming JM,Lin AF,Hussnain SA,Ginsburg E,Vonderhaar BK||Cancer research (70:4624)||2010|