|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Hairy cell leukaemia cells|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay dependent|
|Immunoprecipitation (IP)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-33553 detects CD103 from human samples.
MA1-33553 has been successfully used in immunohistochemistry (frozen tissue), immunoprecipitation, and flow cytometry applications.
The MA1-33553 immunogen is: Hairy cell leukaemia cells
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Subinfectious hepatitis C virus exposures suppress T cell responses against subsequent acute infection.
MA1-33553 was used in flow cytometry to decipher how susequent acute infection is supressed in T cell responses after exposure to subinfectious hepatitis C virus
|Park SH,Veerapu NS,Shin EC,Biancotto A,McCoy JP,Capone S,Folgori A,Rehermann B||Nature medicine (19:1638)||2013|
|Not Applicable||Not Cited||
Higher proliferative capacity of T lymphocytes from patients with Crohn disease than from ulcerative colitis is disclosed by use of Herpesvirus saimiri-transformed T-cell lines.
MA1-33553 was used in flow cytometry to discuss the creation of stable T-cell lines to study their impact in inflammatory bowel disease
|Aguilera-Montilla N,Pérez-Blas M,Valeri AP,López-Santalla M,Rodríguez-Juan C,Mencía A,Castellano G,Manzano ML,Casis B,Sánchez F,Martín-Villa JM||Scandinavian journal of gastroenterology (39:1236)||2004|
|Not Applicable||Not Cited||
Intrinsic defects explain altered proliferative responses of T lymphocytes and HVS-derived T-cell lines in gastric adenocarcinoma.
MA1-33553 was used in flow cytometry to study T-cell lines from gastric cancer patients and healthy volunteers
|Valeri AP,Pérez-Blas M,Gutiérrez A,López-Santalla M,Aguilera N,Rodríguez-Juan C,Sala-Silveira L,Martín J,Lasa I,Mugüerza JM,López A,García-Sancho L,Granell J,Martín-Villa JM||Cancer immunology, immunotherapy : CII (52:708)||2003|
Phenotypic and molecular characterization of CD103+ CD4+ T cells in bronchoalveolar lavage from patients with interstitial lung diseases.
MA1-33553 was used in flow cytometry to test if CD103 has a regulatory role in the microenvironment of the epithelial cell layer.
|Braun RK,Foerster M,Grahmann PR,Haefner D,Workalemahu G,Kroegel C||Cytometry. Part B, Clinical cytometry (54:19)||2003|