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|Tested species reactivity||Chicken, Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Osteoclasts from osteoclastomas.|
|Storage buffer||PBS, pH 7.4|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Flow Cytometry (FACS)||1/50-1/100|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
This antibody does not react with bovine, pig or rabbit.
The epitope recognized by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. We recommend the use of acetone fixation for frozen sections.
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
T-cell leukemia translocation-associated gene (TCTA) protein is required for human osteoclastogenesis.
MA1-80501 was used in immunohistochemistry to study the role of T-cell leukemia translocation-associated gene protein in human osteoclastogenesis
|Kotake S,Nanke Y,Kawamoto M,Yago T,Udagawa N,Ichikawa N,Kobashigawa T,Saito S,Momohara S,Kamatani N,Yamanaka H||Bone (45:627)||2009|
antigen identified by monoclonal antibody L230; integrin alpha-V; integrin alphaVbeta3; integrin beta-3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); platelet membrane glycoprotein IIIa; vitronectin receptor alpha subunit; vitronectin receptor subunit alpha
BDPLT16; BDPLT2; CD51; CD61; GP3A; GPIIIa; GT; MSK8; VNRA; VTNR