|Tested species reactivity||Mouse|
|Published species reactivity||Mouse, Not Applicable|
|Host / Isotype||Armenian hamster / IgG|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
ITGAX is the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Ex vivo induction of antitumor DEC-205(+) CD11c(+) cells in a murine neuroblastoma model by co-stimulation with doxorubicin, lipopolysaccharide and interleukin-4.
MCD11C04 was used in flow cytometry to study ex vivo promotion of antitumor DEC-205(+) CD11c(+) cells in a murine neuroblastoma model by co-stimulation with interleukin-4, lipopolysaccharide, and doxorubicin
|Inoue S,Setoyama Y,Beck Y,Kitagawa D,Odaka A||Biomedical reports (4:27)||2016|
Carbon monoxide reverses adipose tissue inflammation and insulin resistance upon loss of ovarian function.
MCD11c04 was used in flow cytometry to test if carbon monoxide suppresses chronic inflammation and leads to metabolic disturbances
|Choi EK,Park HJ,Sul OJ,Rajasekaran M,Yu R,Choi HS||American journal of physiology. Endocrinology and metabolism (308:E621)||2015|
In vivo transcriptional profiling of Yersinia pestis reveals a novel bacterial mediator of pulmonary inflammation.
MCD11c04 was used in flow cytometry to characterize Yersinia pestis as a novel bacterial mediator of pulmonary inflammation due to in vivo transcriptional profiling
|Pechous RD,Broberg CA,Stasulli NM,Miller VL,Goldman WE||mBio (6:e02302)||2015|
Maternal immune stimulation during pregnancy affects adaptive immunity in offspring to promote development of TH17 cells.
MCD11c04 was used in flow cytometry to examine how maternal immune stimulation affects the adaptive immune system and pathobiology of the offspring
|Mandal M,Marzouk AC,Donnelly R,Ponzio NM||Brain, behavior, and immunity (25:863)||2011|
|Not Applicable||Not Cited||
CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth.
MCD11C04 was used in immunohistochemistry - frozen section to assess the effect of CD40 ligation on the survival of tumor-associated dendritic cells and tumor growth
|Esche C,Gambotto A,Satoh Y,Gerein V,Robbins PD,Watkins SC,Lotze MT,Shurin MR||European journal of immunology (29:2148)||1999|