|Flow Cytometry (Flow)||0.5 ug/test|
|Neutralization (Neu)||See 12 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Immunoprecipitation (IP)||See 1 publications below|
|Flow Cytometry (Flow)||See 2 publications below|
|ELISA (ELISA)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human Beta1 Integrin, the Beta1 chain of the Beta1 integrin heterodimer (CD29)|
MA2910 targets CD29 in FACS applications and shows reactivity with Human samples.
The MA2910 immunogen is human Beta1 Integrin, the Beta1 chain of the Beta1 integrin heterodimer (CD29).
MA2910 detects CD29 which has a predicted molecular weight of approximately 88 kDa.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD29; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; GPIIA; integrin beta 1; Integrin beta-1; integrin VLA-4 beta subunit; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITGB1; MDF2; MSK12; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLA-BETA; VLAB
Gene Aliases: CD29; FNRB; GPIIA; ITGB1; MDF2; MSK12; VLA-BETA; VLAB
UniProt ID: (Human) P05556
Entrez Gene ID: (Human) 3688
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