|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Purified recombinant IFN-alpha 2c.|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Neutralization (Neu)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Alpha interferons are involved in virus resistance. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNa family has pseudogenes in two families (I and II), one with a mature length of 166 aa and one of 172 aa. Cells producing IFN a are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNa include cytopathic effect blocking by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNa are now known and seem to be expressed on most cell types. Three forms of IFN alpha-2 exist; alpha-2a, alpha-2b and alpha-2c.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.