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|Tested species reactivity||Chicken|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant chicken Interferon alpha|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Functional Assay (FN)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
In Western blot, this antibody detects a band at ~19kDa.
The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (INFII). This is not the case for avian IFNs however, even though IFN was first detected in chicken. A growing number of functional studies indicate similarities between chicken IFN and mammilian IFNI, revealing the conservation of cysteine residues and ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.