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|Tested species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG1, kappa|
|Conjugate||Alexa Fluor® 700|
|Storage buffer||PBS with 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
IFN gamma, also called Type II interferon, macrophage activation factor, and immune interferon is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE it appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific and includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFNg is involved in cytokine regulation and also acts synergistically with other cytokines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Increased mucosal CD4+ T cell activation in rhesus macaques following vaccination with an adenoviral vector.
MHCIFG29 was used in flow cytometry to determine if vaccination with a rhesus macaque-derived adenoviral vector simian adenovirus 7 enhances mucosal T cell activation
|Bukh I,Calcedo R,Roy S,Carnathan DG,Grant R,Qin Q,Boyd S,Ratcliffe SJ,Veeder CL,Bellamy SL,Betts MR,Wilson JM||Journal of virology (88:8468)||2014|
IFN-gamma; IFN-y; IFNG; Immune interferon; Interferon gamma; Interferon y; interferon, gamma
IFG; IFI; IFNG