|Tested species reactivity||Mouse|
|Host / Isotype||Armenian hamster / IgG|
|Immunogen||Purified, recombinant mouse interferon gamma.|
|Storage buffer||PBS, pH 7.4|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||0.25-0.5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-24780 detects Interferon gamma from mouse samples.
MA1-24780 has been successfully used in Western blot procedures.
The MA1-24780 immunogen is purified, recombinant mouse interferon gamma. This antibody detects an epitope within residues 15-99 of mouse IFN gamma.
Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.