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|Tested species reactivity||Porcine|
|Published species reactivity||Porcine|
|Host / Isotype||Mouse|
|Immunogen||Recombinant swine interferon-gamma|
|Storage buffer||PBS, pH 7.2|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
IFN gamma, also called Type II interferon, macrophage activation factor, and immune interferon is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE it appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific and includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFNg is involved in cytokine regulation and also acts synergistically with other cytokines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ω-3 PUFA rich camelina oil by-products improve the systemic metabolism and spleen cell functions in fattening pigs.
ASC4839 was used in ELISA to characterize pigs fed camelina oil-cakes
|Taranu I,Gras M,Pistol GC,Motiu M,Marin DE,Lefter N,Ropota M,Habeanu M||PloS one (9:null)||2014|
Effects of zearalenone on oxidative stress and inflammation in weanling piglets.
ASC4839 was used in ELISA to assess pigs that are fed zearalenone.
|Marin DE,Pistol GC,Neagoe IV,Calin L,Taranu I||Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association (58:408)||2013|
Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease.
ASC4839 was used in ELISA to study pigs vaccinated with the emergency inactivated foot-and-mouth disease virus vaccine.
|Barnard AL,Arriens A,Cox S,Barnett P,Kristensen B,Summerfield A,McCullough KC||Vaccine (23:1037)||2005|
Organic barn dust extract exposure impairs porcine macrophage function in vitro: implications for respiratory health.
ASC4839 was used in immunocytochemistry to study the effect of barn dust on swine lung macrophages
|Knetter SM,Tuggle CK,Wannemuehler MJ,Ramer-Tait AE||Veterinary immunology and immunopathology (157:20)||2014|