|Tested species reactivity||Human, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (152 DNDTTPNEELLIERVSH 168) of JAG2 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||5-10 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Protein jagged-2 (JAG2) is a Notch signaling pathway protein which is a ligand for Notch-1. It is a single-pass type 1 membrane protein which contains one DSL domain, sixteen EGF-like domains and one VWFC domain. JAG2, along with JAG1, DLL3 and DLL1 act as predominant Notch ligands, which have overlapping receptor binding specificities. JAG2 is also reported to regulating the expression of cytokines that can promote antitumor immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.