Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: FSAPKDQQVV TAVEYQEAIL ACKTPKKTVS SRLEWKKLGR SVSFVYYQQT LQGDFKNRAE MIDFNIRIKN VTRSDAGKYR CEVSAPSEQG QNLEEDTVTL EVLVAPAVPS CEVPSSALSG TVVELRCQDK EGNPAPEYTW FKDGIRLLEN PRLGSQSTNS SYTMNTKTGT LQFNTVSKLD TGEYSCEARN SVGYRRCPGK RMQVDDLNIS GIIAAVVVVA LVISVCGLGV CYAQRKGYFS KETSFQKSNS SSKATTMSEN DFKHTKSFII
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AU016127; CD322; JAM-2; JAM-B; JAM-IT/VE-JAM; Junctional adhesion molecule 2; Junctional adhesion molecule B; RP23-253E17.2; Vascular endothelial junction-associated molecule; VE-JAM
Gene Aliases: C21orf43; CD322; JAM-B; JAM2; JAMB; PRO245; UNQ219/PRO245; VE-JAM; VEJAM
UniProt ID: (Human) P57087
Entrez Gene ID: (Human) 58494
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support