Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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Immunogen sequence: DIVPEALFLP RRTPTARDNT DVRDFINQRL KENDTDPTAP PYDSLATYAY EGTGSVADSL SSLESVTTDA DQDYDYLSDW GPRFKKLADM YGGVDSDKDS
Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4), whereas kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. Cadherin-6 is expressed in the proximal tubule epithelium of the kidney from which most renal cell carcinomas are derived.
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Protein Aliases: CADH6; cadherin 6, type 2, K-cadherin (fetal kidney); Cadherin-6; Cadherin6; k cadherin; K-cadherin; Kidney cadherin
Gene Aliases: CAD6; cadherin-6; CDH6; K-cadherin; KCAD
UniProt ID: (Human) P55285, (Rat) P55280, (Mouse) P97326
Entrez Gene ID: (Human) 1004, (Rat) 25409, (Mouse) 12563
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