The antibody is specific to KANK1.
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
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Protein Aliases: ankyrin repeat domain 15; Ankyrin repeat domain-containing protein 15; Kidney ankyrin repeat-containing protein; KN motif and ankyrin repeat domain-containing protein 1
Gene Aliases: A930031B09Rik; ANKRD15; AU015049; AW121052; CPSQ2; D330024H06Rik; KANK; KANK1; KIAA0172; mKIAA0172
UniProt ID: (Human) Q14678