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|Tested species reactivity||Human|
|Host / Isotype||Chicken / IgY|
|Immunogen||Purified recombinant KCNJ6 corresponding to the chromosome 21 gene (Human).|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-9548 detects KCNJ6 in human samples.
PA1-9548 has been successfully used in Western blot procedures. By Western blot, PA1-9548 detects a 49 kDa protein representing KCNJ6.
PA1-9548 immunogen is a purified recombinant KCNJ6 corresponding to the chromosome 21 gene (Human).
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
GIRK2; hiGIRK2; inward rectifier K(+) channel Kir3.2; inward rectifier potassium channel KIR3.2; KATP2; KCNJ7; KIR3.2; MGC126596; potassium channel, inwardly rectifying subfamily J, member 6
BIR1; GIRK-2; GIRK2; hiGIRK2; KATP-2; KATP2; KCNJ6; KCNJ7; KIR3.2; KPLBS