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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 61 and 285 of KDM4D (Uniprot ID#Q6B0I6)|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-34882 targets KDM4D in WB applications and shows reactivity with Human samples.
The PA5-34882 immunogen is recombinant fragment corresponding to a region within amino acids 61 and 285 of KDM4D (Uniprot ID#Q6B0I6).
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
jmjC domain-containing histone demethylation protein 3D; JMJD2D; jumonji domain containing 2D; jumonji domain-containing protein 2D; lysine (K)-specific demethylase 4D; lysine-specific demethylase 4D
JHDM3D; JMJD2D; KDM4D