In haemaggulation tests, MA1-80068 reacts with Kp (a-b+) but not Kp (a+b-). This antibody will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but will not react with Ko erythrocytes.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Mouse anti Human CD238 antibody, clone BRIC203 recognizes human CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on the approximately 93 kDa erythrocyte membrane glycoprotein.
This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.
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Protein Aliases: CD238; kell blood group antigen; Kell blood group glycoprotein
Gene Aliases: CD238; ECE3; KEL
UniProt ID: (Human) P23276
Entrez Gene ID: (Human) 3792
Molecular Function: metalloprotease