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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 2 publications below|
MA5-15525 targets KI67 in IHC applications and shows reactivity with Human samples.
The MA5-15525 immunogen is synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH.
MA5-15525 detects KI67 which has a predicted molecular weight of approximately 358kDa.
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Notch3 pathway alterations in ovarian cancer.
MA5-15525 was used in immunohistochemistry to study the role and prognostic value of alterations in Notch3 signaling in ovarian cancer
|Hu W,Liu T,Ivan C,Sun Y,Huang J,Mangala LS,Miyake T,Dalton HJ,Pradeep S,Rupaimoole R,Previs RA,Han HD,Bottsford-Miller J,Zand B,Kang Y,Pecot CV,Nick AM,Wu SY,Lee JS,Sehgal V,Ram P,Liu J,Tucker SL,Lopez-Berestein G,Baggerly KA,Coleman RL,Sood AK||Cancer research (74:3282)||2014|
Prognostic impact of Raf-1 and p-Raf-1 expressions for poor survival rate in non-small cell lung cancer.
MA5-15525 was used in immunohistochemistry to study the prognostic value of Raf-1 and p-Raf-1 expression in non-small cell lung cancer
|Qiu ZX,Wang L,Han J,Liu D,Huang W,Altaf K,Qiu XS,Javed MA,Zheng J,Chen BJ,Li WM||Cancer science (103:1774)||2012|
antigen identified by monoclonal antibody Ki-67; Ki-67; KIA; MKI67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105
KIA; MIB-; MIB-1; MKI67; PPP1R105