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|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15525 targets KI67 in IHC applications and shows reactivity with Human samples.
The MA5-15525 immunogen is synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH.
MA5-15525 detects KI67 which has a predicted molecular weight of approximately 358kDa.
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Mammary serine protease inhibitor and CD138 immunohistochemical expression in ovarian serous and clear cell carcinomas.
MA5-15525 was used in immunohistochemistry - paraffin section to characterize ovarian serous and clear cell carcinomas for CD138 immunohistochemical expression and mammary serine protease inhibitor
|Hasby EA||Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (37:4889)||2016|
Notch3 pathway alterations in ovarian cancer.
MA5-15525 was used in immunohistochemistry to study the role and prognostic value of alterations in Notch3 signaling in ovarian cancer
|Hu W,Liu T,Ivan C,Sun Y,Huang J,Mangala LS,Miyake T,Dalton HJ,Pradeep S,Rupaimoole R,Previs RA,Han HD,Bottsford-Miller J,Zand B,Kang Y,Pecot CV,Nick AM,Wu SY,Lee JS,Sehgal V,Ram P,Liu J,Tucker SL,Lopez-Berestein G,Baggerly KA,Coleman RL,Sood AK||Cancer research (74:3282)||2014|
Prognostic impact of Raf-1 and p-Raf-1 expressions for poor survival rate in non-small cell lung cancer.
MA5-15525 was used in immunohistochemistry to study the prognostic value of Raf-1 and p-Raf-1 expression in non-small cell lung cancer
|Qiu ZX,Wang L,Han J,Liu D,Huang W,Altaf K,Qiu XS,Javed MA,Zheng J,Chen BJ,Li WM||Cancer science (103:1774)||2012|
antigen identified by monoclonal antibody Ki-67; Antigen KI-67; Ki-67; KIA; MKI67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105
KIA; MIB-; MIB-1; MKI67; PPP1R105