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Product Details
MA5-50468
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2269
Immunogen
Recombinant fragment of human KLF5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3093834
Target Information
KLF5 is a member of the Kruppel-like factor subfamily of zinc finger proteins. It contains three C2H2-type zinc fingers at the carboxyl-terminus that preferentially bind to cis-DNA elements that are GC rich. KLF5 is a transcription activator that promotes cell proliferation and oncogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (intestinal Kruppel-like factor; basic transcription element binding protein 2; basic transcription element binding protein BTEB2; Basic transcription element-binding protein 2; BTE-binding protein 2; Colon krueppel-like factor; colon kruppel-like factor; GC box binding protein 2; GC-box-binding protein 2; Intestinal-enriched krueppel-like factor; intestinal-enriched kruppel-like factor; Klf5C isoform; Krueppel-like factor 5; Kruppel-like factor 5 (intestinal); RP11-505F3.5; Transcription factor BTEB2
Gene Aliases: 4930520J07Rik; BTEB2; CKLF; IKLF; KLF5
UniProt ID: (Human) Q13887, (Mouse) Q9Z0Z7
Entrez Gene ID: (Human) 688, (Rat) 84410, (Mouse) 12224
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
metal ion binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
sequence-specific DNA binding
nucleic acid binding
C2H2 zinc finger transcription factor
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
transcription from RNA polymerase II promoter
microvillus assembly
regulation of microvillus assembly
skeletal muscle cell differentiation
positive regulation of fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
intestinal epithelial cell development
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
positive regulation of transcription, DNA-templated
cellular response to organic cyclic compound
cellular response to peptide
transcription, DNA-templated
regulation of transcription, DNA-templated
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